Study: Increased intake of omega-3 fatty acids may protect against advanced prostate cancer

According to findings published in the journal Clinical Cancer Research, the fatty acids may work by modifying a specific variant of the COX-2 gene,a known inflammatory gene.  The variant is linked to a five-fold increased risk of advanced prostate cancer, report the researchers, but individuals with high intakes of omega-3 may have a reduced risk, even if they carried the COX-2 variant.

The COX-2 increased risk of disease was essentially reversed by increasing omega-3 fatty acid intake by a half a gram per day.

“Previous research has shown protection against prostate cancer, but this is one of the first studies to show protection against advanced prostate cancer and interaction with COX-2,” said lead researcher Professor John Witte. “The COX-2 increased risk of disease was essentially reversed by increasing omega-3 fatty acid intake by a half a gram per day.” This study adds to a growing body of evidence linking fish consumption and omega-3 to potential cancer benefits.

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